Agent skill

Biomaster

by ai4nucleome in ai4nucleome/BioMaster

BioMaster conversational bioinformatics assistant; starts workflows only after execution intent or empty activation.

No licenceAuto-check passedResearch & Science

Install Biomaster

skills CLI
$ npx skills add ai4nucleome/BioMaster --skill biomaster -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install ai4nucleome/BioMaster biomaster --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/ai4nucleome/BioMaster.git skills-src && mkdir -p .claude/skills && cp -r skills-src/.opencode/skills/biomaster .claude/skills/biomaster && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
biomaster
GitHub stars
115
Token cost
~2.1k tokens
SKILL.md length
951 words
Files
1
Skills in repo
1
Repo updated
First seen
Licence
None found

At a glance

BioMaster conversational bioinformatics assistant; starts workflows only after execution intent or empty activation.

  • Works in 2 steps: First ask for the analysis objective in… → After the objective is clear, ask for…
  • Tasks that involve Bioinformatics
  • SKILL.md covers Hard Gates, Initial Response Language, OpenCode Choice Policy and Boundaries
  • Instructions only: no scripts, shell commands, URLs or credentials in SKILL.md

What it does

Biomaster is an agent skill from ai4nucleome/BioMaster. BioMaster conversational bioinformatics assistant; starts workflows only after execution intent or empty activation.

Its SKILL.md is about 2.1k tokens, which your agent loads only when the skill is triggered. It is a single SKILL.md file with no bundled scripts. Compatibility notes: opencode

It sits in Research & Science, covering Bioinformatics. It works with SQLite.

When your agent uses it

  • Tasks that involve Bioinformatics

Example prompts

  • “/biomaster”

Requirements

  • Python 3
  • Compatibility (from SKILL.md): opencode

Workflow steps

2 steps, taken from the first numbered list in SKILL.md.

  1. First ask for the analysis objective in English. Offer a few broad examples only, such as differential analysis, cell annotation, survival…
  2. After the objective is clear, ask for input files in English. Request data paths, file types, sample metadata, grouping variables, and any…

What it can do on your machine

Read from SKILL.md and the folder at commit 6f98a63. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    No scripts in the folder and no shell commands in SKILL.md (its code samples are markdown).

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    No URLs in SKILL.md.

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

  • Compatibility

    opencode

    From compatibility in the SKILL.md frontmatter.

Context cost

Biomaster loads about 2.1k tokens when it runs. Until then it costs about 32 tokens; SKILL.md has 951 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~32
When it runs · the whole SKILL.md, loaded when a task matches
~2.1k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

Without a licence we can't republish the file, so here is its outline and opening line. It has 951 words (~2,072 tokens).

“BioMaster is a conversational bioinformatics assistant. It can answer general questions, explain methods, discuss BioSkills knowledge, help maintain workflow or execution knowledge entries, and start structured analyses when the user is ready to execute a task.”

— opening of SKILL.md by ai4nucleome
name
biomaster
compatibility
opencode
metadata.layer
registry
metadata.domain
bioinformatics
metadata.status
active

Read the full SKILL.md on GitHub

Files

Just SKILL.md in .opencode/skills/biomaster of ai4nucleome/BioMaster.

Open the folder on GitHubat commit 6f98a63

Compare with similar skills

Biomaster next to the 5 skills that share the most tags, products or categories with it. Stars are the repository's; “used in” counts other GitHub owners with a copy.

Biomaster compared with similar skills
SkillStarsUsed inTokensAuto-checkLicenceRepo updated
Biomaster this skillai4nucleome/BioMaster115—~2.1kAutomated safety check: PassNone
Bio Read SequencesFreedomIntelligence/OpenClaw-Medical-Skills3.1k1 repos~2.6kAutomated safety check: PassNone
Bioconductor DrugtargetinteractionsbioMate-AI/biomate-bioconductor-kb804—~1.2kAutomated safety check: PassCustom licence
Bio Genome Intervals Gtf Gff HandlingGPTomics/bioSkills1.2k1 repos~4.6kAutomated safety check: PassMIT
Alphagenome Single Variant Analysisgoogle-deepmind/science-skills3.2k2 repos~3kAutomated safety check: NotesApache-2.0
13C Metabolic Flux AnalysisK-Dense-AI/scientific-agent-skills48k1 repos~3.2kAutomated safety check: PassMIT

Similar skills

  • Bio Read Sequences

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    Read biological sequence files (FASTA, FASTQ, GenBank, EMBL, ABI, SFF) using Biopython Bio.SeqIO.

    3.1k GitHub starsUsed in 1 repo~2.6k tokens
    Research & ScienceAuto-check passed
  • Bioconductor Drugtargetinteractions

    bioMate-AI/biomate-bioconductor-kb

    Provides utilities for identifying drug-target interactions for sets of small molecule or gene/protein identifiers.

    804 GitHub stars~1.2k tokensUpdated 3 mo ago
    Research & ScienceAuto-check passed
  • Parses, queries, converts, and extracts from GTF and GFF3 gene-model annotation files - walking the gene/transcript/exon/CDS hierarchy with gffutils (queryable SQLite DB), converting formats and…

    1.2k GitHub starsUsed in 1 repo~4.6k tokens
    Data & AnalyticsAuto-check passed
  • Alphagenome Single Variant Analysis

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    Analyzes genetic variant effects on gene expression (RNA-seq), chromatin accessibility (DNASE), histone marks (ChIP), and transcription factors using the AlphaGenome API.

    3.2k GitHub starsUsed in 2 repos~3k tokens
    Research & ScienceAuto-check: notes
  • 13C Metabolic Flux Analysis

    K-Dense-AI/scientific-agent-skills

    Estimates reaction fluxes inside cells from steady-state carbon-13 labeling data with a bundled mfapy-based solver, and reports which fluxes the data pin down.

    48k GitHub starsUsed in 1 repo~3.2k tokens
    Research & ScienceAuto-check passed
  • Clinvar Database

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    A skill your agent uses when needing clinical significance, pathogenicity classifications (e.g., Pathogenic, Benign, VUS), clinical evidence rationales, or finding "hard positive" benchmark controls…

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    Research & ScienceAuto-check: notes

Works with

Questions about Biomaster

What does Biomaster do?

BioMaster conversational bioinformatics assistant; starts workflows only after execution intent or empty activation. Biomaster is an agent skill from ai4nucleome/BioMaster. BioMaster conversational bioinformatics assistant; starts workflows only after execution intent or empty activation.

When should I use Biomaster?

Biomaster fits situations like: tasks that involve Bioinformatics.

How do I install Biomaster in Claude Code?

Run `npx skills add ai4nucleome/BioMaster --skill biomaster -a claude-code`. Or copy the skill folder (.opencode/skills/biomaster in ai4nucleome/BioMaster) into .claude/skills/biomaster in your project. Claude Code loads it when a task matches its description.

How do I install Biomaster in Codex?

Run `npx skills add ai4nucleome/BioMaster --skill biomaster -a codex`. Or copy the skill folder (.opencode/skills/biomaster in ai4nucleome/BioMaster) into .agents/skills/biomaster in your project. Codex loads it when a task matches its description.

Can I use Biomaster in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add ai4nucleome/BioMaster --skill biomaster -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/biomaster, .gemini/skills/biomaster, .github/skills/biomaster and .opencode/skills/biomaster in your project.

What does Biomaster need to run?

SKILL.md names no scripts, command-line tools or credentials: Biomaster is instructions for the agent only. Our summary lists: Python 3. Compatibility (from SKILL.md): opencode.

Does Biomaster access the network?

SKILL.md contains no URLs. Any network use would come from the scripts or tools the agent runs. This is read from the text; nothing was executed.

Is Biomaster safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Biomaster use?

No licence was found for Biomaster or its repository. Without one, default copyright applies: ask the author before reusing or redistributing it.

How many tokens does Biomaster use?

About 2.1k tokens (SKILL.md is roughly 8.3k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full.

What are the alternatives to Biomaster?

Skills that share tags, products or a category with Biomaster: Bio Read Sequences (FreedomIntelligence/OpenClaw-Medical-Skills, 3.1k stars), Bioconductor Drugtargetinteractions (bioMate-AI/biomate-bioconductor-kb, 804 stars), Bio Genome Intervals Gtf Gff Handling (GPTomics/bioSkills, 1.2k stars) and Alphagenome Single Variant Analysis (google-deepmind/science-skills, 3.2k stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Biomaster?

ai4nucleome (a GitHub organization) maintains it in ai4nucleome/BioMaster, which has 115 GitHub stars. The repository was last updated on July 14, 2026.

Source: ai4nucleome/BioMaster on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.