Agent skill

Fda Catalyst Vaccines

by agentii-ai in agentii-ai/agentii-investment-intelligence

Vaccine catalyst analysis across the two-gate path: CBER BLA review and the ACIP recommendation gate that turns FDA approval into commercial availability.

Apache-2.0Auto-check passedBusiness, Finance & HR

Install Fda Catalyst Vaccines

skills CLI
$ npx skills add agentii-ai/agentii-investment-intelligence --skill fda-catalyst-vaccines -a claude-code

Project install by default; add -g for ~/.claude/skills/.

GitHub CLI
$ gh skill install agentii-ai/agentii-investment-intelligence fda-catalyst-vaccines --agent claude-code

Project scope by default; add --scope user for a personal install. Needs GitHub CLI 2.90.0 or later (public preview).

Manual copy
$ git clone --depth 1 https://github.com/agentii-ai/agentii-investment-intelligence.git skills-src && mkdir -p .claude/skills && cp -r skills-src/plugins/vertical-plugins/bio-pharm/skills/agentii/fda-catalyst-vaccines .claude/skills/fda-catalyst-vaccines && rm -rf skills-src

Use ~/.claude/skills/ instead of .claude/skills for a personal install. The folder must contain SKILL.md.

Claude Code skills documentation · loads skills from .claude/skills/

Facts

Skill name
fda-catalyst-vaccines
GitHub stars
207
Token cost
~1.9k tokens
SKILL.md length
724 words
Files
3 (incl. references)
Skills in repo
79
Repo updated
First seen
Licence
Apache-2.0

At a glance

Vaccine catalyst analysis across the two-gate path: CBER BLA review and the ACIP recommendation gate that turns FDA approval into commercial availability.

  • Works in 4 steps: ACIP gate data: search_acip_events /… → FDA/CBER track: get_upcoming_pdufa /… → Panel and filing context:… → …
  • Tasks that involve Vendor and procurement management
  • SKILL.md covers Defaults, Preflight, Triggers and Production Grounding, plus 11 more sections
  • Instructions only: no scripts, shell commands, URLs or credentials in SKILL.md

What it does

Fda Catalyst Vaccines is an agent skill from agentii-ai/agentii-investment-intelligence. Vaccine catalyst analysis across the two-gate path: CBER BLA review and the ACIP recommendation gate that turns FDA approval into commercial availability. Lot release, procurement milestones, pediatric bridging, and healthy-population efficacy context — dated, verified, and sized per event.

Its SKILL.md is about 1.9k tokens, which your agent loads only when the skill is triggered. The skill folder holds 3 other files, including reference files (for example `references/knowledge-frameworks.md` and `references/modes.md`).

It sits in Business, Finance & HR, covering Vendor and procurement management and Project management. The repository describes itself as: Claude-type skills for institutional equity research — 25 AI agent skills with SEC filings, XBRL financials, earnings calendars, DCF/comps/LBO models, and PPT generation. Powered… The licence is Apache-2.0.

When your agent uses it

  • Tasks that involve Vendor and procurement management
  • Tasks that involve Project management

Example prompts

  • “/fda-catalyst-vaccines”

Workflow steps

4 steps, taken from the first numbered list in SKILL.md.

  1. ACIP gate data: search_acip_events / get_acip_event (vote counts, status ladder).
  2. FDA/CBER track: get_upcoming_pdufa / search_fda_approvals (BLA events).
  3. Panel and filing context: search_adcom_meetings (VRBPAC) + search_documents / search_sec_filings for procurement and lot-release…
  4. Historical grounding: search_investment_cases (acip_vote/approval events), search_by_analogue.

What it can do on your machine

Read from SKILL.md and the folder at commit 86980e1. It shows what the files ask for, not the result of running them.

  • Tool permissions

    Pre-approves nothing: there is no allowed-tools line, so your agent's usual permission prompts apply.

    From allowed-tools in the SKILL.md frontmatter.

  • Runs code

    No scripts in the folder and no shell commands in SKILL.md.

    From the folder's file list and the shell code blocks in SKILL.md.

  • Network

    No URLs in SKILL.md.

    From URLs in SKILL.md, links to its own repository left out.

  • Credentials

    Names no API keys, tokens, secrets or passwords.

    From names ending in _API_KEY, _TOKEN, _SECRET, _KEY or _PASSWORD in SKILL.md.

Context cost

Fda Catalyst Vaccines loads about 1.9k tokens when it runs, and up to ~3.2k if it reads all its reference files. Until then it costs about 78 tokens; SKILL.md has 724 words of instructions outside code blocks.

Always · name and description, kept in context so the agent knows when to use it
~78
When it runs · the whole SKILL.md, loaded when a task matches
~1.9k
With references · SKILL.md plus every file in references/, read only if the agent opens them
~3.2k

Estimates: characters ÷ 4, the usual rule of thumb; real counts depend on the model's tokenizer. Scripts and assets cost tokens only if the agent reads them.

Safety

Auto-check passed

The automated check found no risky patterns in SKILL.md.

Automated static check — not a guarantee. Review scripts before installing. It scans the text of SKILL.md for risky patterns (piping downloads into a shell, reading credential files, hidden Unicode, destructive commands); files beside SKILL.md are not scanned.

SKILL.md

The full file from agentii-ai/agentii-investment-intelligence at commit 86980e1, republished under its Apache-2.0 licence (© agentii-ai). 724 words, ~1,882 tokens.

Download SKILL.mdSave it as .claude/skills/fda-catalyst-vaccines/SKILL.md (or your agent's skills folder). This skill also uses 2 other files; get the full folder from GitHub.
name
fda-catalyst-vaccines
description
Vaccine catalyst analysis across the two-gate path: CBER BLA review and the ACIP recommendation gate that turns FDA approval into commercial availability. Lot release, procurement milestones, pediatric bridging, and healthy-population efficacy context — dated, verified, and sized per event.
sectors
med.medicines_biotech, med.medical_devices
multi_ticker_semantics
basket_v1_1
temporal_scope.default_quarters
4
temporal_scope.max_quarters
8
temporal_scope.description
Forward catalyst window default 4 quarters; up to 8 for multi-season campaign and bridging cycles.
retrieval_scope
unstructured_document_search
min_tool_diversity
3
parameter_free
false

Methodology inspired by publicly taught vaccine commercial frameworks; all text is an original paraphrase.

Defaults

ParameterDefault ValueRationale
forward_window_quarters4Standard catalyst window; extend to 8 on request
include_supersededfalseActive-only events by default; supersede chains on request
acip_gatetrueACIP status always shown next to FDA decisions — approval is not availability
procurement_lenstrueGovernment purchasing and campaign milestones tracked
holiday_labelingtrueHoliday-shifted weeks flagged on every calendar row

Preflight

Run canonical pre-flight per contracts/preflight.md. Include the X-Agentii-Trace header on every tool call per contracts/x-agentii-trace-header.md — carry the _run_id from your first tool result and name yourself (and your parent, if you were spawned). Confirm ticker resolution via search_companies before catalyst queries.

Triggers

  • "When is [vaccine]'s ACIP meeting, and what is the vote outlook?"
  • "Is [vaccine] FDA-approved but still awaiting an ACIP recommendation?"
  • "What does the ACIP vote mean for [ticker]'s commercial launch?"
  • "What procurement milestones are pending for [vaccine/ticker]?"
  • "When is lot release expected for [vaccine]?"
  • "What pediatric or age-cohort bridging studies are pending?"
  • "Build a vaccine catalyst calendar for my watchlist."
  • "Which vaccine decisions land this quarter?"
  • "How do ACIP recommendation categories change uptake?"
  • "What happens between FDA approval and commercial availability?"
  • "Which vaccine catalysts overlap with [ticker]'s earnings date?"
  • "How did similar vaccines trade around their ACIP votes?"

Production Grounding

  • Two-gate path: FDA approval (CBER BLA) is necessary but not sufficient — the ACIP row (scheduled → voted → adopted) is the gate data, with CDC Director sign-off and MMWR publication distinct steps from the vote.
  • ACIP recommendation categories (routine / catch-up / risk-based / shared-clinical-decision-making) set the uptake ceiling; votes move stocks like PDUFA dates move drug names.
  • CBER context: healthy-population efficacy bar (large N, safety-first), lot-release testing, and manufacturing capacity as a catalyst in its own right.
  • Procurement milestones: government stockpiles and purchase contracts (doses/serials, procurement value), seasonal campaign timing.
  • Pediatric bridging, booster cycles, and age-cohort expansions re-open the catalyst window after launch.
  • Holiday-week labeling discipline: campaign-week comps are noisy; label holiday weeks explicitly. Never fabricate votes, dates, or procurement values (per references/knowledge-frameworks.md).

Data Source Priority

  1. ACIP gate data: search_acip_events / get_acip_event (vote counts, status ladder).
  2. FDA/CBER track: get_upcoming_pdufa / search_fda_approvals (BLA events).
  3. Panel and filing context: search_adcom_meetings (VRBPAC) + search_documents / search_sec_filings for procurement and lot-release disclosures.
  4. Historical grounding: search_investment_cases (acip_vote/approval events), search_by_analogue.

Methodology

Retrieval Scope

unstructured_document_search

Retrieval Strategy
  1. Resolve ticker(s) via search_companies; note vaccine product names.
  2. Pull ACIP events (search_acip_events) and FDA-track dates (get_upcoming_pdufa); pair them per product.
  3. For each ACIP event, retrieve vote detail (get_acip_event by vaccine + meeting date) and panel context.
  4. Layer procurement and lot-release milestones from filings (search_sec_filings 8-Ks, search_documents).
  5. Ground the play: search_investment_cases / search_by_analogue with vaccine filters; cite /v/ records.
Show full SKILL.md (284 more words)Show less
Temporal Scope

See frontmatter temporal_scope block. Seasonal campaigns may require looking back up to 8 quarters.

Tool Allowlist

See frontmatter allowed_tools.

Protocol
  1. Ticker resolution
  2. Two-gate enumeration (FDA date + ACIP row per product)
  3. Per-event vote framing (recommendation category + history)
  4. Procurement and lot-release overlay
  5. Calendar synthesis + commercial-availability flags

Modes

  • Watchlist (default, multi-ticker): one dated calendar with per-ticker sections, sorted by date.
  • Single ticker deep-dive: full two-gate timeline per vaccine + procurement state.
  • ACIP gate: approval-to-recommendation transition tracking across names.

Tool Fallbacks

FailureFallback
search_acip_events emptysearch_documents keyword ACIP + search_sec_filings; annotate coverage_gap
No ACIP row for a productFlag the unmodeled commercial step explicitly; never assume approval = launch
Procurement data missingState purchase-contract data unavailable; do not estimate values
Knowledge tools emptyProceed with structured data only; annotate knowledge coverage_gap

Output File

{ticker}/{YYYY-MM-DD_HHMM}_fda-catalyst-vaccines_{affix}.md (watchlist: watchlist/{YYYY-MM-DD_HHMM}_fda-catalyst-vaccines-calendar_{affix}.md)

Output Structure

  1. Executive Summary — highest-impact vaccine catalysts in the window, 2-3 sentences
  2. Two-Gate Calendar — dated table: date, ticker, product, FDA event, ACIP row, holiday-week flag, availability framing
  3. Per-Event Analysis — vote context (recommendation category, committee read) + decision history
  4. Procurement & Lot Release — contracts, stockpile status, campaign timing
  5. Historical Analogues — matched vaccine cases with /v/ citations and quantified outcomes
  6. Risk Assessment & Coverage Gaps — binary-risk sizing, two-gate failure modes, missing data

Error Handling

ErrorFallback
No ACIP or PDUFA rowsFall back to earnings + pipeline events; annotate coverage_gap — never fabricate dates
Approval without ACIP rowPresent the gap as the central risk; do not imply commercial availability
Ticker not in med universeResolve via CIK/vaccine-universe match; surface the classification gap

Memory Load

See contracts/memory-load.md.

Snapshot

See contracts/snapshot-synthesis.md.

Final Summary (TUI)

Include ### Key Citations block with 0-10 clickable /v/ URLs.

References

  • contracts/citation-and-memory.md
  • contracts/output-frontmatter-schema.md
  • contracts/memory-load.md
  • contracts/snapshot-synthesis.md
  • contracts/preflight.md
  • references/knowledge-frameworks.md

© agentii-ai, Apache-2.0. Rendered from Markdown: HTML in the file is shown as text, images as links, and headings moved down two levels. Raw file

Files

SKILL.md and 2 other files (references) in plugins/vertical-plugins/bio-pharm/skills/agentii/fda-catalyst-vaccines of agentii-ai/agentii-investment-intelligence.

  • SKILL.md
  • references/knowledge-frameworks.md
  • references/modes.md

Open the folder on GitHubat commit 86980e1

Compare with similar skills

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Fda Catalyst Vaccines compared with similar skills
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Ceos Calendarbradfeld/ceos156—~2kAutomated safety check: PassMIT

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Questions about Fda Catalyst Vaccines

What does Fda Catalyst Vaccines do?

Vaccine catalyst analysis across the two-gate path: CBER BLA review and the ACIP recommendation gate that turns FDA approval into commercial availability. Fda Catalyst Vaccines is an agent skill from agentii-ai/agentii-investment-intelligence. Vaccine catalyst analysis across the two-gate path: CBER BLA review and the ACIP recommendation gate that turns FDA approval into commercial availability.

When should I use Fda Catalyst Vaccines?

Fda Catalyst Vaccines fits situations like: tasks that involve Vendor and procurement management; tasks that involve Project management.

How do I install Fda Catalyst Vaccines in Claude Code?

Run `npx skills add agentii-ai/agentii-investment-intelligence --skill fda-catalyst-vaccines -a claude-code`. Or copy the skill folder (plugins/vertical-plugins/bio-pharm/skills/agentii/fda-catalyst-vaccines in agentii-ai/agentii-investment-intelligence) into .claude/skills/fda-catalyst-vaccines in your project. Claude Code loads it when a task matches its description.

How do I install Fda Catalyst Vaccines in Codex?

Run `npx skills add agentii-ai/agentii-investment-intelligence --skill fda-catalyst-vaccines -a codex`. Or copy the skill folder (plugins/vertical-plugins/bio-pharm/skills/agentii/fda-catalyst-vaccines in agentii-ai/agentii-investment-intelligence) into .agents/skills/fda-catalyst-vaccines in your project. Codex loads it when a task matches its description.

Can I use Fda Catalyst Vaccines in Cursor, Gemini CLI or GitHub Copilot?

Cursor, Gemini CLI, GitHub Copilot and OpenCode also load SKILL.md folders. With the skills CLI, run `npx skills add agentii-ai/agentii-investment-intelligence --skill fda-catalyst-vaccines -a cursor` (or -a gemini-cli, github-copilot or opencode for the others). To copy it by hand, put the folder in .cursor/skills/fda-catalyst-vaccines, .gemini/skills/fda-catalyst-vaccines, .github/skills/fda-catalyst-vaccines and .opencode/skills/fda-catalyst-vaccines in your project.

What does Fda Catalyst Vaccines need to run?

SKILL.md names no scripts, command-line tools or credentials: Fda Catalyst Vaccines is instructions for the agent only.

Does Fda Catalyst Vaccines access the network?

SKILL.md contains no URLs. Any network use would come from the scripts or tools the agent runs. This is read from the text; nothing was executed.

Is Fda Catalyst Vaccines safe to install?

Our automated static check of SKILL.md found no risky patterns, such as piping downloads into a shell, reading credential files or hidden Unicode. It is not a guarantee. Review the folder before installing.

What licence does Fda Catalyst Vaccines use?

Fda Catalyst Vaccines is published under the Apache-2.0 licence (the repository's licence). It allows redistribution, so the full SKILL.md is shown on this page.

How many tokens does Fda Catalyst Vaccines use?

About 1.9k tokens (SKILL.md is roughly 7.5k characters). Agents keep only the skill's name and description in context until a task matches; then they load SKILL.md in full. Its references folder adds about 1.3k tokens, read only when the agent opens those files.

What are the alternatives to Fda Catalyst Vaccines?

Skills that share tags, products or a category with Fda Catalyst Vaccines: SaaS Vendor Inventory (mukul975/Privacy-Data-Protection-Skills, 301 stars), Iclr Workflow (brycewang-stanford/Awesome-Journal-Skills, 1.2k stars), Serenity Alpha (haskaomni/serenity-skill, 633 stars) and Scorecard Matrix (pnp/sharepoint-skills, 133 stars). The comparison table on this page puts their stars, adoption, token cost, safety result and licence side by side.

Who maintains Fda Catalyst Vaccines?

agentii-ai (a GitHub user) maintains it in agentii-ai/agentii-investment-intelligence, which has 207 GitHub stars. The repository holds 79 skills in this directory. The repository was last updated on September 29, 2026.

Source: agentii-ai/agentii-investment-intelligence on GitHub. Facts on this page come from the repository at the commit we read; the author's words are quoted as theirs.